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jove.com
Video: Nitriles to Amines: LiAlH4 Reduction
3.8K Views. Nitriles are reduced to amines in the presence of strong reducing agents like lithium aluminum hydride through a typical nucleophilic acyl substitution. The reaction requires two equivalents of the reducing agent. The reducing agent acts as a source of hydride ions. As shown below, the mechanism involves three steps. Firstly, the ...
Nov 2, 2024
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