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11:49
YouTube
Yigong Shi Lab
Mechanistic Understanding of Pre-mRNA Splicing by the Spliceosome
Pre-messenger RNA (pre-mRNA) splicing is a crucial and the most complex step in the central dogma in eukaryotic cells. This process is executed by a dynamic mega-complex known as the spliceosome. Recent atomic-resolution structures of the intact spliceosome at different stages advanced mechanistic understanding of pre-mRNA splicing. This ...
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