In the human genome, the fraction of synonymous codons changes monotonically with the GC content of coding sequences: with increasing the GC content the codons that are richer in GC within their ...
Whole-genome recoding has been shown to enable nonstandard amino acids, biocontainment and viral resistance in bacteria. Here we take the first steps to extend this to human cells demonstrating ...
Combining MAGE with CAGE allowed the genome to manipulated as an editable and evolvable template. Scientists have combined a recently developed technique known as multiplex automated genome ...
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