A single genetic mutation can lead to completely different diseases, depending on the time and location at which the mutation occurs. This finding emerged from the PhD study conducted by Rocio ...

Real-world data demonstrate non-classical mutations are present in 20-30% of all patients with EGFRm NSCLC Emerging data show non-classical EGFR mutations can be co-expressed with the classical L858R ...

Analyses of patients with non-classical EGFR mutations reveal that the majority receive frontline chemotherapy and the remainder are treated with osimertinib or afatinib Short time to treatment ...

A study completed at the University of Helsinki and the Folkhälsan Research Center analysed 390 parent–offspring trios. Trio denotes a design where the genomes of the puppy and both parents are ...

A separate, albeit less pronounced, maternal effect was also observed. In terms of size, large breeds appeared to accumulate relatively more early-life mutations, while the number of de novo mutations ...