As python hunters head out into the Everglades for the 2026 Florida Python Challenge, many of them will feel the bite of the invasive snake.

Let's start with that skull: The bones are connected by elastic ligaments, which have a lot of stretch. And teeth? A snake's teeth are angled toward the throat and act as hooks to prevent live prey ...

Back in January, Burmese python hunter Carl Jackson caught one of the heaviest pythons on record in Florida. His catch, a 16-foot, 10-inch female python hiding in the Big Cypress National Preserve, ...

While Burmese pythons are not venomous, their bites are common and feel like needles tearing through the skin. Invasive pythons have severely impacted Florida's small mammal populations in the ...