Loss of GATA6—a transcription factor that controls which genes are turned on or off—can reprogram colorectal cancer cells ...
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the ...
IN THE POPULAR imagination, cancer starts with a mutation in the DNA of a normal cell. That mutation allows the cell to multiply uncontrollably, circumventing the body’s usual quality-control checks.
Immunotherapies – treatments that aim to make the body's natural immune system more effective – are becoming more widely used ...
A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that ...
Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...
A first-in-class nanoparticle injection sneaks antibodies into pancreatic cancer cells to clear mutant KRAS, shrinking tumors ...