Genetic diseases that result from truncated proteins can be targeted by so-called nonsense suppression therapies—drugs that prevent protein translation from terminating prematurely. A new ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at ...

A study on how aging impacts the brain in killifish has found that getting old selectively impairs the production of some key DNA- and RNA-binding proteins. And this change contributes to hallmarks of ...

Long-standing research has shown that consuming dietary protein stimulates muscle protein synthesis, which is a critical factor for building and maintaining skeletal muscle mass. Growing evidence has ...