LpxC inhibitors target a zinc-dependent deacetylase that catalyses the first committed step in lipid A biosynthesis, an essential process for the viability of Gram-negative bacteria. As lipid A forms ...

There are two main types of bacteria, and these categories reflect the microbes' biology and their vulnerability to different antibiotics. When you purchase through links on our site, we may earn an ...

Like all living things, bacteria adapt to survive. Over time, bacteria have been developing resistance to common antibiotics and disinfectants, which poses a growing problem for health care and ...

The emergence of multi-drug resistance bacteria and healthcare-associated infections are frequent issues in the treatment of suppurating wounds. A group of researchers has created a bactericidal ...

In a recent study published in the journal Nature, researchers in the United States of America designed and discovered lolamicin, a selective antibiotic that targets the lipoprotein transport system ...

Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...