Osteoarthritis (OA) is a common joint disease that involves cartilage degradation, bone remodeling, osteophyte formation, angiogenesis, and synovial inflammation [1]. In the early stages of OA, ...
This is due to epigenetic components: microRNA, histone and DNA methylation, gene mutations that alter the expression and production of the neurotrophic factor BDNF, which interacts with the receptors ...
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