New machine-learning tool improves accuracy of genomics research

University of Virginia School of Medicine scientists have identified a widespread source of error in a popular method for ...
GEN

Can CUT&RUN and CUT&Tag Replace ChIP-Seq?

CUT&RUN and CUT&Tag assays are dramatically changing how scientists perform chromatin mapping experiments by providing high-quality data using low cell inputs and sequencing depths. Some have ...
Fred Hutch

New method quickly, precisely maps epigenome in single cells

Scientists at Fred Hutchinson Cancer Research Center have published a new method that allows investigators to map chromatin — the DNA modifications, packaging proteins and molecular factors that work ...
GEN

New CUT&Tag Approach Profiles Chromatin Modifications in Single Cells

There is an explosion of single-cell genomics profiling technologies. Although major advances have been made in measuring gene expression and DNA accessibility, assays specific to epigenetic ...
Fred Hutch

Single-cell CUT&Tag to identify cell states in normal and disease tissue

Genes turning “on” and “off”’ during development is key for cell lineage determination. The signal to switch off gene expression on delineated genomic regions is a chromatin modification: trimethyl ...