Stem cells are defined by their self-renewal and multilineage differentiation capacities. Postnatally, multiple types of lineage-restricted stem cells have been defined in different tissues and organs ...

Monogenic disorders of bone mass arise from variants in single genes disrupting the intricate processes of bone formation and resorption. Genes underlying bone mass disorders are involved in various ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

Scientists have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced. The study also shows that movement-induced stimulation is ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...